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DeCS
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Descriptor English:
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Wnt-5a Protein
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Descriptor Spanish:
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proteína Wnt5a
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Descriptor Portuguese:
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Proteína Wnt-5a
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Synonyms English:
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Wingless Type MMTV Integration Site Family, Member 5A
Wingless-Type MMTV Integration Site Family, Member 5A
Wnt 5a Protein
Wnt5a Protein
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Tree Number:
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D12.776.467.984.050
D12.776.624.664.700.962
D23.529.984.050
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Definition English:
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A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56635
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Unique Identifier:
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D000071818
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Occurrence in VHL:
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Similar:
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DeCS
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